Lithuto tse Ncha li Hlalosa Mabaka le Liphekolo tsa Maqeba a Mali a Amanang le COVID-19

Leha e le lefu la phefumoloho haholo, COVID-19 e bonts'itsoe e baka likarabelo tse fapaneng, ho kenyeletsoa le litlamorao tse mpe tsamaisong ea pelo. Bakuli ba bang ba bontšitse karabelo ea ho ruruha e ka bakang thrombosis, mme ho na le ts'oaetso e phahameng ho ba nang le bokuli bo matla.

Pampiring ea pele, bafuputsi Univesithing ea Pennsylvania ba supile bakena-lipakeng ba bohlokoa ba ho ruruha le lefu la pelo ho bakuli ba COVID-19 ba amanang hantle le ts'ebetso ea platelet tsamaisong ea BioFlux. Sehlopha se boetse se bonts'itse hore Syk inhibitor fostamatinib e khutlisa matla a matla a platelet litekong tsa BioFlux. Bafuputsi ba fihletse qeto ea hore sena se emela mokhoa o ikhethileng, o lebeletsoeng oa ho fetola phello ena.

Pampiring ea bobeli, bafuputsi ba Univesithi ea Tuebingen ba bonts'itse hore maemo a fokotsehileng a cAMP (cyclic adenosine monophosphate) liplateleteng a ile a eketsa ho kopana ha li-antibody-induced platelet coagulation le ho thehoa ha thrombus. Liphello tsena li ne li thibetsoe ke Iloprost, e leng moemeli oa phekolo ea amohelehang oa tleliniki e eketsang maemo a intracellular cAMP liplatelete.

Lipampiri ka bobeli li ne li itšetlehile ka sistimi ea BioFlux ho lekola tšebetso ea platelet ho bakuli ba COVID-19. Sistimi ea BioFlux e sebetsa joalo ka "artery on chip" e laolang ka nepo tikoloho e nyane ea sele ho etsisa maemo a 'mele oa motho, e fana ka sethala se loketseng bakeng sa lipatlisiso tsa tšebetso ea mali e amanang le COVID-19. E sebelisoa lilaboratoring tse fetang 500 lefatšeng ka bophara, sistimi ea BioFlux e fumaneha ka mefuta e fapaneng ea litlhophiso ho fihlela litlhoko tsa ts'ebeliso ea laboratoring efe kapa efe. Litsamaiso li fumaneha ka mefuta e mengata ea bokhoni le liphetho 'me li sebelisoa lipatlisisong tsa mantlha ka ho sibolla lithethefatsi le nts'etsopele ea tlhahlobo.

 

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