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$32 Million Grant ho Ithuta Lefu la Alzheimer

ngotsoeng ke mohlophisi

Ho thusa ho sebetsana le leqhubu le ntseng le phahama la lefu la Alzheimer naheng ka bophara, bafuputsi ba Albert Einstein College of Medicine ka tšebelisano le lefapha la thuto ea matsoho Univesithing ea Pennsylvania State le litsi tse ling, ba fumane chelete ea lilemo tse hlano, $32 milione ho tsoa ho National Institutes of Health (NIH) ho tshehetsa Thuto ya Botsofadi ya Einstein (EAS), e shebaneng le botsofadi bo tlwaelehileng le diphephetso tse ikgethang tsa lefu la Alzheimer, le dementia e meng. EAS e thehiloe Einstein ka 1980 mme esale e tšehelitsoe ka lichelete ke NIH.      

"Lilemong tsa rona tse leshome tsa bohlano tsa Thuto ea Botsofali ea Einstein, re boemong bo botle ba ho haha ​​​​holim'a liphuputso tsa rona tsa pejana ho tseba litsela tsa ho lieha ho qala le ho hatela pele ha lefu la Alzheimer," ho boletse Richard Lipton, MD, ea etelletseng pele kapa hammoho ho ithuta ho tloha 1992 mme ke Edwin S. Lowe Moprofesa oa Neurology, moprofesa oa kelello le mahlale a boitšoaro, le oa lefu la seoa & bophelo bo botle ba baahi. Hape ke motlatsi oa molula-setulo oa thuto ea boko ho Einstein le Montefiore Health System. 

Hammoho le Dr. Lipton, nchafatso e etelletsoe pele ke Carol Derby, Ph.D., moprofesa oa lipatlisiso Lefapheng la Neurology la Saul R. Korey le lefapheng la lefu la seoa le bophelo bo botle ba baahi, le Louis le Gertrude Feil Faculty Scholar in Neurology. ho Einstein. Dr. Derby esale e le moetapele oa morero ho EAS ka lilemo tse fetang leshome. Sehlopha sa boetapele se boetse se kenyelletsa Orfeu Buxton, Ph.D., Elizabeth Fenton Susman Moprofesa oa Biobehavioral Health Univesithing ea Pennsylvania State.

Meroalo le ho se lekane ha Dementia

United States, batho ba fetang karolo ea boraro ea batho ba ka holimo ho lilemo tse 85 ba na le lefu la Alzheimer, e leng sesosa sa bohlano se ka sehloohong sa lefu har'a batho ba lilemo tse 65 le ho feta. Batho ba ka bang limilione tse 6.5 ba ka holimo ho lilemo tse 65 ba tšoeroe ke lefu lena kajeno-palo eo ho boleloang esale pele hore e tla atamela ho limilione tse 13 ka 2050.

Joalo ka mafu a mangata le maemo a bophelo bo botle, ho se lekane ha merabe le merabe ho amahanngoa le lefu la Alzheimer's. Dr. Lipton o re: “Maamerika a Matšo a na le monyetla oa ho tšoaroa ke lefu la Alzheimer ka makhetlo a imenneng habeli ho feta balekane ba ’ona ba basoeu, ’me Ma-Hispanics le ’ona a kotsing e khōloanyane ea lefu lena,” ho boletse Dr. Lipton. "Ho feta moo, tlhahlobo ea mafu hangata e liehisoa lichabeng tsena tse neng li qheletsoe ka thoko. Re hloka ho etsa betere le ho fumana litsela tsa ho rarolla liphapang tsena. ”

EAS e ithutile ho feta baahi ba Bronx ba 2,500 ba lilemo tse 70 le ho feta. E boemong bo ikhethang ba ho hlahloba lintlha tse amanang le ho se lekane, ka lebaka la mefuta-futa ea barupeluoa ba eona. Hajoale, 40% ke bao e seng ba Ma-Hispanic Black, 46% ke ba basoeu bao e seng ba Ma-Hispanic, 'me 13% ke Ma-Hispanic.

Dr. Derby o itse: “Sepheo se seng sa phuputso ea rōna ke ho hlahloba hore na matla a sechaba a tlatsetsa joang ho se lekane ha bophelo bo botle ba kelello. "Ho bohlokoa hore re hlahlobe hore na morabe, morabe, maemo a boahelani le khethollo ke mabaka a kotsi a ho fokotseha ha kelello le lefu la Alzheimer."

Ho kenella ho Theknoloji

Lilemong tse hlano tse fetileng, EAS e nkile monyetla oa thekenoloji ea thelefono ho fumana lintlha tse e-s'o ka tsa e-ba teng ka boko bo tsofalang. "Nakong e fetileng, re ile ra hlahloba temoho ka ho khetheha ka liteko tsa motho ka mong ka laboratoring ea rona ea bongaka," ho boletse Mindy Joy Katz, MPH, motsoalle ea phahameng Lefapheng la Neurology la Saul R. Korey Einstein le mohokahanyi oa morero oa EAS. "Ka ho fa barupeluoa ba rona li-smartphone, re khona ho lekanya ts'ebetso ea kelello ka kotloloho ha ba ntse ba etsa mesebetsi ea letsatsi le letsatsi sechabeng."

Thuso e ncha e tla lumella bafuputsi ba EAS ho latela batho ba baholo ba 700 Bronx ba fetang lilemo tse 60 ba lulang hae. E mong le e mong ea nkang karolo thutong o tla fuoa smartphone e ikhethileng bakeng sa libeke tse peli selemo se seng le se seng. Sesebelisoa se tla ba hlokomelisa hangata ka letsatsi ho araba lipotso mabapi le liphihlelo tsa bona tsa letsatsi le letsatsi le boemo ba kelello le ho bapala lipapali tse lekanyang temoho ea bona.

Nakong ena ea libeke tse peli, barupeluoa ba tla boela ba roale lisebelisoa tse hlokomelang mosebetsi oa bona oa 'mele, boroko, maemo a tsoekere ea mali, le ho lekanya tšilafalo ea moea le maemo a mang a tikoloho. Bafuputsi ba tla sebelisa lintlha tsena ho fumana hore na maemo a kotsi a ama joang ts'ebetso ea nako e khuts'oane le ea nako e telele ea kelello. Ba tla boela ba hlahlobe mabaka a kotsi a lefutso le li-biomarker tse thehiloeng maling ho hlakisa litsela tse hokahanyang mabaka a kotsi ho liphello tsa kelello le nts'etsopele ea lefu la Alzheimer's.

Ho nka litekanyo khafetsa ka matsatsi a mangata ho e-na le ho bala laboratoring e le 'ngoe "ho re fa kutloisiso ea 'nete ea bokhoni ba motho ba kelello [ea ho nahana] le hore na bokhoni boo bo fetoha joang letsatsi le letsatsi, bophelong ba bona ba letsatsi le letsatsi," Mme Katz o boletse. "Mekhoa ena e boetse e re lumelletse ho latela batho ho pholletsa le seoa sena, ha maeto a bona a ne a sa sireletseha."

Qetellong, sepheo sa thuto ke ho khetholla lintlha tse lebisang liphellong tse mpe tsa kelello bakeng sa motho ka mong, ebe, haeba ho khoneha, ho fetola maemo ao a kotsi ho thibela 'dementia' ho hōla. “Re a itse gore go na le mabaka a a farologaneng—a tsa kalafi, a loago, a boitshwaro, a tikologo—a a thusang go tlhagolela bolwetse jwa Alzheimer,” go ne ga bolela jalo Dr. Derby. "Ka ho soma liphihlelo tsa motho e mong le e mong, re tšepa hore ka letsatsi le leng re tla fana ka liphekolo tse tloaelehileng tse tla thusa batho ho boloka bophelo bo botle ba kelello le ho lula ba phetse hantle kelellong ho fihlela lilemong tsa bona tsa morao."

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mohlophisi

Mohlophisi e moholo oa eTurboNew ke Linda Hohnholz. O lula ntlong e kholo ea eTN e Honolulu, Hawaii.

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