Ho ea ka ADx Health, "Ho makatsang ke hore batho ba arolelana 99% ea liphatsa tsa lefutso tse tšoanang. Karolo ea 1% e ikhethang e akarelletsa liphetoho metheong e itseng ea nucleotide, e leng se fellang ka liphetoho liphatseng tse itseng tsa lefutso, ’me maemong a mang, ho fetoha ha likotsi tsa mafu a itseng,” ho akarelletsa le kotsi ea lefu la Alzheimer.
Hona joale ho lumeloa ka bophara hore lefu la Alzheimer le bakoa ke maemo a kotsi a ka fetoloang (joalo ka phepo e nepahetseng, boikoetliso, boroko) le tse sa fetoheng (liphatsa tsa lefutso, lilemo, thobalano). Le hoja APOE e le eona e tsebahalang haholo ea lefutso e amanang le kotsi ea lefu la Alzheimer, GenoRisk polygenic test e hlahloba liphatsa tsa lefutso tse 29 ho phaella ho APOE.
Leha ho le joalo, liphuputso tse ngata tsa lipatlisiso li kile tsa sebelisa kotsi ea liphatsa tsa lefutso tsa APOE ho hlahloba lihlooho, ho siea likheo tse kholo ho utloisisa setšoantšo se feletseng sa ho bolela kotsi bakeng sa AD, ke ka lebaka leo ADx Health e ileng ea hlahisa mokhoa o mocha oa ho hlahloba lefu la Alzheimer ka tlhahlobo ea GenoRisk.
Lintlha tsa boithuto ba GenoRisk li bonts'a hore ho ka ba le likotsi tse fapaneng ka har'a mofuta o fanoeng oa APOE. Maemong a mang, batho ba nang le mofuta o tlase oa kotsi ea APOE ba kanna ba ba le kotsi e kholo ea liphatsa tsa lefutso ho feta motho ea nang le mefuta e mengata ea kotsi ea APOE ka lebaka la ho kenyelletsa lilemo le phetoho ea thobalano.
"Ka kutloisiso e betere ea hore na liphatsa tsa lefutso tse ngata li sebelisana joang ho bolela kotsi ea AD, mofuta ona oa tlhahlobo ea polygenic o ka fana ka kutloisiso e kholo ho tsamaiso ea Alzheimer ka bomong, ho kenyelletsa le hore na bakuli ba tšoaroa joang, liphello tsa liteko tsa meriana, le mehato ea ho fokotsa kotsi", ho boletse Ryan Fortna. , MD, e mong oa bangoli ba thuto.
