Tlhahiso e Kholo ea Meriana ea Molomo oa COVID-19 le Liteko

Hajoale, COVID-19 e ntse e le maemong a seoa lefatšeng ka bophara. Bophahamo ba mefuta e fapaneng ea Delta le Omicron bo jele setsi, bo bakang ntlafatso e tsoelang pele ea bokhoni ba bona ba phetisetso. Har'a maqhubu a pheta-phetoang a COVID-19, ntle le ente ea COVID-19, nts'etsopele ea litlhare tse sebetsang tsa molomo tsa COVID-19 le mekhoa e potlakileng, e bonolo le e ncha ea tlhahlobo le eona e fetohile tlhoko e ncha ea thibelo le taolo ea seoa sa hajoale. Viva Biotech Holdings XLement, e tsetelitsoeng le ho kenyeletsoa ke Viva BioInnovator, e ikemiselitse ho hlahisa lithethefatsi tsa molomo tsa COVID-19 le tlhahlobo ea vaerase, ho kenya letsoho ntoeng khahlanong le seoa sa COVID-19.

Ka Pherekhong 2022, Medicines Patent Pool (MPP) e phatlalalitse hore e saenetse litumellano le lik'hamphani tse 'maloa tse etsang lihlahisoa tse tloaelehileng ho kenyeletsoa Zhejiang Langhua Pharmaceutical Co., Ltd., e leng setsi sa Viva biotech holdings bakeng sa ho etsa moriana oa antiviral oa molomo oa COVID-19 molnupiravir le. phepelo linaheng tse 105 tse nang le moputso o tlase le o mahareng (LMICs) ho thusa phihlello e fumanehang ea lefats'e bakeng sa molnupiravir le ho ts'ehetsa thibelo le taolo ea seoa sa lehae. Lik'hamphani tse hlano li tla shebana le ho hlahisa metsoako e tala, lik'hamphani tse 13 li tla hlahisa motsoako o tala le setlhare se felileng 'me lik'hamphani tse 9 li tla hlahisa moriana o felileng.

Letamo la Patent ea Meriana (MPP) ke mokhatlo oa bophelo bo botle ba sechaba o tšehelitsoeng ke Machaba a Kopaneng o sebetsang ho eketsa phihlello, le ho thusa ho nts'etsopele ea, meriana e pholosang bophelo bakeng sa linaha tse nang le meputso e tlase le e bohareng. MPP le MSD, lebitso la khoebo la Merck & Co., Inc Kenilworth NJ USA e saenetse tumellano ea boithaopo ea laesense ka Oct 2021. Tlas'a lipehelo tsa tumellano, MPP, ka laesense e fanoeng ke MSD, e tla lumelloa ho ntšetsa pele laesense ntle le khetho. ho fana ka lilaesense ho bahlahisi le ho fapanyetsana motheo oa tlhahiso bakeng sa phepelo ea molnupiravir e netefalitsoeng ke boleng linaheng tse tlas'a Laesense ea MPP, ho ipapisitsoe le tumello ea taolo ea lehae.

Molnupiravir (MK-4482 le EIDD-2801) ke mofuta oa lipatlisiso, o tsamaisoang ka molomo oa analoge e matla ea ribonucleoside e thibelang phetisetso ea SARS-CoV-2 (e leng sesosa sa COVID-19). Molnupiravir eo MSD e ntseng e e nts'etsapele ka ts'ebelisano 'moho le Ridgeback Biotherapeutics, ke moriana oa pele o nooang oa antiviral o fumanehang bakeng sa kalafo ea COVID-19. Lintlha tse tsoang ho Mokhahlelo oa 3 MOVe-OUT li bonts'itse hore kalafo ea pele ka molnupiravir e fokotsa haholo kotsi ea ho kena sepetlele kapa lefu le kotsing e kholo, batho ba baholo ba sa entoeng ba nang le COVID-19.

Ho ea ka MPP, lik'hamphani tse ileng tsa fuoa mangolo a tlaase li bontšitse ka katleho bokhoni ba tsona ba ho finyella litlhoko tsa MPP tse amanang le bokhoni ba tlhahiso, ho latela melao, le bokhoni ba ho finyella litekanyetso tsa machaba tsa meriana e tiisitsoeng ka boleng. Tumello e filoeng Langhua Pharmaceutical ke MPP e emela tiiso e phahameng le kananelo ho nts'etsopele ea eona ea ts'ebetso le ho holisa li-API, phepelo ea phepelo, GMP le sistimi ea EHS.

Ka la 2 Hlakubele 2022, Xlement, k'hamphani e inehetseng ea NanoSPR ea biochip le lisebelisoa tsa biotech eo pele e neng e tsetela le ho kengoa ke Viva BioInnovator, e amohetse tsebiso ea ho fetisa tlhahlobo ea ts'ebetso ho tsoa Lefapheng la Saense le Thekenoloji la People's Republic of China. Morero oa eona oa "R&D and Mass Production of NanoSPR COVID-19 Particle Test Kit" ke e 'ngoe ea merero ea bohlokoa ea "Thibelo le Taolo ea Kotsi ea Ts'ireletso ea Sechaba le Lenaneo la Karabelo ea Tšohanyetso le Thepa" e sebetsang karolo ea bohlokoa ho COVID-19- liphuputso tse amanang le saense tse ntseng li tsoela pele Chaena. Ka katleho e atlehileng ea tlhahlobo, Xlement's COVID-19 Test Kit le eona e netefalitsoe ke European Union CE bakeng sa tlhahiso e kholo ea nako e tlang mme e tla qala ho sebelisoa haufinyane.

Ka lebaka la theknoloji e ikhethang ea NanoSPR chip, Xlement e ile ea hlahisa lisebelisoa tsa liteko bakeng sa likaroloana tsa COVID-19, tse lumellang teko ea mohato o le mong oa li-antigen tse ngata tsa kokoana-hloko bakeng sa lisampole tse 96 nakong ea metsotso e 15, 'me kutloisiso e haufi le ho leka antigen e le' ngoe. Mokhoa ona o bontša melemo e meholo ha e bapisoa le mekhoa e teng ea tlhahlobo ea kokoana-hloko ea nucleic acid: e ka sebelisoa bakeng sa ho itlhahloba lapeng, e khutsufatsa nako ea teko haholo, kahoo, e fokotsa haholo litšenyehelo tsa ho hlahloba li-reagents le mosebetsi. Ka kamohelo e eketsehileng ea theknoloji ea NanoSPR tekong ea COVID-19 e ntlafalitsoeng ke Xlement, re lebelletse ho bona tlhahlobo e bonolo ea kapele ea lisampole tse belaelloang le tlhahlobo e potlakileng ea setšeng ka bongata bo boholo.