Litaba tsa mohala

Kalafo e Ncha ea Lipatlisiso bakeng sa Kankere ea Boko

ngotsoeng ke mohlophisi

Setsi sa Kankere sa John Theurer Setsing sa Bongaka sa Univesithi ea Hackensack se phatlalalitse kajeno hore se alafa mokuli oa pele ka har'a naha ka DSP-0390, setlhare se secha sa lipatlisiso sa glioblastoma (GBM) le li-gliomas tse ling tsa anaplastic.         

Glioblastoma (GBM) ke e 'ngoe ea mefuta e mabifi ka ho fetisisa ea mofetše oa boko o atisang ho ipheta ho sa tsotellehe mekhoa e tloaelehileng ea phekolo e kang chemotherapy le radiation. Ho phela ka mor'a lilemo tse hlano ha hoa tloaeleha, 'me phekolo e ncha e hlokahala haholo.

DSP-0390, moemeli e mocha oa lipatlisiso o entsoeng ke Cambridge, Massachusetts-based Sumitomo Dainippon Pharma Oncology, ke inhibitor ea emopamil-binding protheine (EBP), molek'hule ho cholesterol biosynthesis. DSP-0390 ha e so amoheloe ke Tsamaiso ea Lijo le Lithethefatsi ea US ebile ha e so thehoe polokeho le katleho ea eona.

"'Mele ea rona e hloka k'holeseterole ho haha ​​​​lisele tse phetseng hantle le hore lisele tseo li tšoaetsane," ho boletse Samuel A. Goldlust, MD, Mookameli oa Bongaka oa Neuro-Oncology. "Empa lisele tsa GBM li ka qobella tlhahiso ea k'holeseterole ho feta tekano, e leng se lebisang ho holeng ha hlahala le ho thibela EPB ho ka thibela kholo ena."

Boithuto bona ba lefatše ka bophara ba Phase 1/2 bo reretsoe ho ngolisa bakuli ba 70 litsing tse hlano tsa hlahala ea boko US le Japane.

Kopano ea maeto a lefats'e ka bophara Mmaraka oa maeto oa Lefatše London o khutlile! Mme o memilwe. Ona ke monyetla oa hau oa ho hokahana le basebetsi-'moho le uena indastering, marang-rang a lithaka, ho ithuta lintlha tsa bohlokoa le ho fihlela katleho ea khoebo ka matsatsi a 3 feela! Ngolisa ho boloka sebaka sa hau kajeno! e tla etsahala ho tloha ka la 7-9 Pulungoana 2022. Ngodisa hona joale!

"Liteko tsa bongaka tsa GBM li re rutile hore phekolo ea setso ha ea lekana ho hlōla hlahala ena e phephetsang," ho boletse George J. Kaptain MD, Mookameli oa Neurosurgical Oncology. "Ke tokelo ho khona ho fa bakuli ba rona monyetla oa ho fumana litlhare tse mabapi le limolek'hule tse kang DSP -0390, ts'ebetsong ea rona e tsoelang pele ea kalafo ho thusa ho phela le ho fokotsa litlamorao."

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mohlophisi

Mohlophisi e moholo oa eTurboNew ke Linda Hohnholz. O lula ntlong e kholo ea eTN e Honolulu, Hawaii.

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