Phekolo e Ncha ea Thibelo ea liphoofolo tse tšoaelitsoeng ke Omicron

Aridis Pharmaceuticals, Inc., k'hamphani ea biopharmaceutical e shebaneng le ho sibolloa le nts'etsopele ea litlhare tse thibelang tšoaetso ho phekola mafu a sokelang bophelo, e phatlalalitse kajeno hore li-antibodies tsa eona tsa "monoclonal" tsa motho (mAbs) ka har'a lebenkele la AR-701 li ile tsa fokotsa SARS. -CoV-2 Omicron e fapaneng. Ho feta moo, li-mAbs ka bobeli li fana ka tšireletso e felletseng khahlano le liphoofolo tse tšoaelitsoeng ke Omicron ha li fanoa ka botsoali kapa ka tsamaiso ea intranasal. 

• Ka bobeli li-mAbs ho AR-701 cocktail, ke hore, AR-720 le AR-703, li felisitse mefuta eohle ea 'nete ea SARS-CoV-2 beta, gamma, delta, epsilon, le Omicron in vitro

• Ka bobeli li-mAbs tsa AR-701 cocktail, ha li sebelisoa ka bonngoe kapa li kopane, li fane ka pheliso e feletseng ea kokoana-hloko ho litoeba tse tšoaelitsoeng ke Omicron le tšireletso khahlanong le lefu la mafu.

Aridis Pharmaceuticals e sa tsoa amohela lithuso tsa $ 1.9 milione (USD) ho tsoa ho Bill le Melinda Gates Foundation ho lekola thibelo ea feberu le phetiso ea vaerase ea SARS-CoV-2 (COVID-19) e sebelisa phepelo e huloang ea li-antibodies tsa monoclonal.

"Re lumela hore liphetho tsena tse khahlisang tsa katleho ea liphoofolo ke tsa pele lenaneong lefe kapa lefe la COVID-antibody ho bonts'a boemo bona ba ts'ebetso e pharalletseng le katleho, ho kenyeletsoa le mefuta e tšoaelitsoeng ea Omicron. Ka lebaka la lintlha tse kholo tsa kliniki tse tsoang ho ba bang tse bonts'itseng hore mAbs e sebetsa joalo ka kalafo e thibelang COVID-19, re nahana hore AR-701 e maemong a matle bakeng sa pan-coronavirus prophylaxis ” ho boletse Vu Truong, Ph.D., CEO oa Aridis Pharmaceuticals. "Ntle le ho sebetsa ka thata khahlanong le mefuta eohle ea COVID-19, re kile ra bonts'a katleho ea AR-701 khahlano le SARS, MERS, le livaerase tsa ntaramane ea nako ea selemo, 'me ho bohlokoa haholo, e etselitsoe katleho ea nako e telele, e ka nkang selemo kapa ho feta. ha e sebelisoa ho batho,” ho tsoela pele Dr. Truong. "AR-701 ke e 'ngoe ea mananeo a mangata a monate a phaephe ea rona e fapaneng, e kenyelletsang mananeo a mabeli a Mokhahlelo oa 3 ho pneumonia ea baktheria le lenaneo la Phase 2 ho cystic fibrosis. Re labalabela ho arolelana lintlha tse ling ha re ntse re tsoela pele ho ntšetsa pele mananeo ana. ”