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New Digital Pathology e Fumana Lefu la Parkinson la Pele-Mothati

ngotsoeng ke mohlophisi

PreciseDx, e sa tsoa tsoa Mount Sinai Health System e New York, NY, ke eona feela k'hamphani ea Cancer Risk Stratification e fanang ka tlhahisoleseling e tobileng ea bakuli ka tlhahlobo ea likarolo tsa morphology. Kajeno k'hamphani e phatlalalitse theknoloji ea eona ea AI-enabled digital pathology e ka hlahloba ka nepo lefu la Parkinson (PD) ho bakuli ba phelang pele matšoao a hlaha.

Ho hlahlobisisa lefu la Parkinson ho thata ka linako tsohle ka lebaka la matšoao a fapaneng, ho kula le maemo a ho etsisa, 'me tlhahlobo e hlakileng e tla feela kamora lefu la lefu. Boithuto bona ba bohlokoa bo fumane hore theknoloji ea PreciseDx e nolofalitsoeng ke AI e khona ho thusa tlhahlobo e felletseng ea Parkinson's, e fanang ka tlhaiso-leseling e bohlokoa bakeng sa kalafo ea pejana.

"Liphuputso tsena li bontša bokhoni ba theknoloji ho thusa ho hlahloba lefu la Parkinson," ho boletse Jamie Eberling, PhD, Motlatsi oa Motlatsi oa Motlatsi oa Lipatlisiso ho The Michael J. Fox Foundation bakeng sa Patlisiso ea Parkinson (MJFF). "Lisebelisoa tsa tlhahlobo ea sepheo, haholo-holo qalong ea lefu, li bohlokoa ho tsamaisa liqeto tsa tlhokomelo le ho rala liteko tse lebisang ho liphekolo le liphekolo tse betere."

MJFF e ile ea tšehetsa tlhahlobo ea AI ka chelete e itseng 'me ea tšehetsa boithuto bo faneng ka data (Systemic Synuclein Sampling Study).

Boithuto ba PreciseDx bo sebelisitse li-algorithms tsa k'hamphani (Morphology Feature Array™) bakeng sa tlhahlobo ea IHC ea α-synuclein ka har'a methapo ea methapo ea litšoelesa tsa mathe [ke hore, peripheral Lewy-type synucleinopathy (LTS)], hammoho le ho ntšoa ha likarolo tse ngata ho sebelisa likarolo tsa morphology ho ho khetholla ka nepo LTS mefuteng ea pele ea lefu la Parkinson's biopsy e ipapisitseng le tlhaloso ea setsebi sa mafu a lisampole tsa koetliso. Ka mor'a koetliso, tlhahlobo ea algorithmic e ile ea tiisoa ho sebelisoa sete e fapaneng ea mehlala e tiisitsoeng ea biopsy.

PreciseDx's AI Morphology Feature Array e khonne ho bona lefu la Parkinson lipacheng tsa litšoantšo ho tsoa lisampoleng tsa biopsy tse nang le kutlo ea 99% le 99% e ikhethang ha e bapisoa le 'nete e boletsoeng ke litsebi. AI e ile ea hlakisa ngaka ea mafu a batho ka nepo ea 0.69 khahlano le 0.64 ponelopeleng ea boemo ba lefu la Parkinson.

Mokhoa oa MFA oa PreciseDx oa ho hlahisa tlhahiso le tlhahlobo o thusa li-algorithms tse ncha ho nts'etsopele le ho netefatsoa khahlano le liphetho tsa bongaka. Sena se bohlokoa haholo ho theha liteko tse ncha tsa tlhahlobo, tlhahlobo e nepahetseng le e ka hlahisoang hape, prognosis, khetho ea mokuli ea kalafo bakeng sa maemo a fapaneng a fapaneng.

"Ka tloaelo, litsamaiso tsa boemo ba pathology li sheba likarolo tse 'maloa tsa morphology ho etsa tlhahlobo. Ho fapana le mokhoa leha e le ofe oa ho hlophisa o sebelisoang ke motho, PreciseDx's AI Morphology Feature Array (MFA) e ka hlahloba likarolo tse likete tse fapaneng le ho matlafatsa likamano tseo pakeng tsa tsona, "ho boletse John F. Crary, MD-PhD, Moprofesa Lefapheng la Pathology, Neuroscience, le Artificial Intelligence & Human Health Sekolong sa Bongaka sa Icahn se Thabeng ea Sinai. "Phuputso ena e fetolang indasteri e bontšitse hore re hloka ho tsosolosa tsela eo re nahanang ka lefu la mafu le ho itšetleha ka ho sebelisa AI ho lemoha mafu ka nepo, joalo ka PD. Sena se khantša indasteri phuputsong e tobileng mabapi le hore na lefu la computational le ka ntšetsa pele meriana joang mabapi le ho khetholla le ho lemoha mafu ka nepo. ”

"Re labalabela ho sebetsa le PreciseDx ha e ntse e hlahloba bokhoni ba ho sebelisa sethala sa AI ho mafu ho mafu a mangata, ho akarelletsa le Parkinson," ho boletse Erik Lium, PhD, Mopresidente, Mount Sinai Innovation Partners le Motlatsi oa Motlatsi oa Mookameli le Mookameli ea ka Sehloohong oa Innovation ea Khoebo, Sistimi ea Bophelo ea Mount Sinai.

Theknoloji ea stratification ea mofetše e ipapisitse le thepa ea mahlale e ntlafalitsoeng ke lefapha la Mount Sinai mme e fuoe laesense ea PreciseDx. Lefapha la Mount Sinai le Mount Sinai li na le thahasello ea lichelete ho PreciseDx. Thaba ea Sinai e boetse e na le boemeli ho PreciseDx Board of Directors, e kenyeletsang Dr. Lium.

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mohlophisi

Mohlophisi e moholo oa eTurboNew ke Linda Hohnholz. O lula ntlong e kholo ea eTN e Honolulu, Hawaii.

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